| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8223559 | International Journal of Radiation Oncology*Biology*Physics | 2013 | 8 Pages |
Abstract
Hepatocytes were the major determinants of the hypoxic microenvironment and radioresponse of CRC cells in our model of metabolic hypoxia. We provide evidence that reoxygenation and radiosensitization of hypoxic CRC cells can be achieved through oxygen sparing induced by endogenous NO production in host hepatocytes.
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Authors
Heng MS, Valeri N. PhD, Wim MS, Ka Lun BS, Marieke PhD, Guy MD, PhD, Dirk MD, Thierry MSc, Alexandra MD, Mark MD, PhD,