| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8223938 | International Journal of Radiation Oncology*Biology*Physics | 2012 | 8 Pages |
Abstract
MRI can detect regional differences in neuroanatomy and brain growth after whole-brain irradiation in the developing mouse. Developmental deficits in neuroanatomy persist, or even progress, and may serve as useful markers of late effects in mouse models. The high-throughput evaluation of brain development enabled by these methods may allow testing of strategies to mitigate late effects after pediatric cranial irradiation.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Lisa M. PhD, Kyle BSc, Fred G. PhD, Jason P. PhD, C. Shun MD, Brian J. PhD,