Article ID Journal Published Year Pages File Type
8225289 International Journal of Radiation Oncology*Biology*Physics 2012 8 Pages PDF
Abstract
Inhibition of Aurora B kinase with low AZD1152-HQPA concentrations during irradiation of NSCLC cell lines affects repopulation during radiotherapy. Thus, concomitant Aurora B kinase inhibition and irradiation may be a promising strategy for fast repopulating tumors, which are difficult to cure by dose escalation based on conventional fractionation.
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Related Topics
Physical Sciences and Engineering Physics and Astronomy Radiation
Preview
Inhibiting the Aurora B Kinase Potently Suppresses Repopulation During Fractionated Irradiation of Human Lung Cancer Cell Lines
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