Article ID Journal Published Year Pages File Type
8226103 International Journal of Radiation Oncology*Biology*Physics 2012 9 Pages PDF
Abstract
Combined treatment with UCN-01 and celecoxib can exert synergistically enhanced radiosensitizing effects via cooperative inhibition of the ionizing radiation-activated G2 checkpoint. We propose that this combination strategy may be useful in clinical applications of UCN-01 for radiotherapy of cancer patients.
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Related Topics
Physical Sciences and Engineering Physics and Astronomy Radiation
Preview
Celecoxib Enhances the Radiosensitizing Effect of 7-Hydroxystaurosporine (UCN-01) in Human Lung Cancer Cell Lines
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