Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8226530 | International Journal of Radiation Oncology*Biology*Physics | 2012 | 9 Pages |
Abstract
Increased PTEN signaling after radiation results in apoptosis of lung parenchymal cells. We hypothesize that upregulation of PTEN is influenced by Nox4-derived oxidative stress. To our knowledge, this is the first study to highlight the role of PTEN in radiation-induced pulmonary toxicity.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Yu Zhang, Xiuwu M.D., Ph.D., Zahid N. M.D., Isabel L. B.S., Zeljko M.D., Ph.D.,