Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8226719 | International Journal of Radiation Oncology*Biology*Physics | 2012 | 7 Pages |
Abstract
Tumor regions with highest MRglc are characterized by high cellular uptake and phosphorylation rate constants with relatively low blood volume fractions. In regions with less metabolic activity, the blood volume fraction increases and cellular uptake, washout, and phosphorylation rate constants decrease. These results support the hypothesis that regional tumor glucose phosphorylation rate is not dependent on the transport of nutrients (i.e., FDG) to the tumor.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Dennis M.D., Jonathan A. Ph.D., Wim J.G. M.D., Ph.D., Lioe-Fee M.D., Ph.D., Eric P. Ph.D.,