Improved Outcomes of Breast-Conserving Therapy for Patients With Ductal Carcinoma in Situ

In an era of mammographically identified DCIS, larger excisions, widely negative margins and the use of a tumor bed boost, we observed no LR regardless of ER/PR/HER-2 status. Factors associated with HER-2+DCIS included more extensive DCIS, Grade III, ER−/PR−, central necrosis, comedo subtype, and postmenopausal status. Further follow-up and additional studies are required to confirm these results.