Osteoradionecrosis in Head-and-Neck Cancer Has a Distinct Genotype-Dependent Cause

Article ID	Journal	Published Year	Pages	File Type
8227237	International Journal of Radiation OncologyBiologyPhysics	2012	6 Pages	PDF

Abstract

Our findings support the postulate that the development of ORN is related to the presence of the T variant allele at -509 within the TGF-Î²1 gene.

Keywords

Post-radiotherapy Variant allele Osteoradionecrosis Transforming growth factor-β1 Head-and-neck cancer Genotype

Related Topics

Physical Sciences and Engineering Physics and Astronomy Radiation

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Osteoradionecrosis in Head-and-Neck Cancer Has a Distinct Genotype-Dependent Cause

Authors

Andrew J. M.S., F.R.C.S., Catharine M. Ph.D., Janet M. Ph.D., Nick J. F.R.C.R., Clara F.R.C.R., Siobhan M.Sc., Gabrielle Ph.D., Dawn B.Sc., Richard J. M.D., F.D.S., F.R.C.S.,