Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8229022 | International Journal of Radiation Oncology*Biology*Physics | 2011 | 9 Pages |
Abstract
These data indicate that radioresistance of K-RAS mutated tumor cells is at least in part due to constitutive production of EGFR ligands, which mediate enhanced repair of DNA double-strand breaks through the EGFR-phosphatidylinositol-3-kinase-Akt cascade.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Minjmaa M.Sc., Mahmoud Ph.D., Rainer Ph.D., Klaudia Ph.D., H. Peter Ph.D.,