Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8230206 | International Journal of Radiation Oncology*Biology*Physics | 2011 | 9 Pages |
Abstract
Activation of Shh signaling protects HCC cells against ionizing radiation in an autocrine manner. Impairment of DNA damage repair might involve mechanism of Shh-induced radioresistance. Targeting Shh signaling pathway may be a novel strategy to enhance the radioresponse of human HCC cells.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Yu-Jen M.D., Ph.D., Chin-Ping M.S., Ming-Ling B.S., Hui-Ru B.S., Nicholas K. Chao, K.S. Clifford M.D.,