| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8232173 | International Journal of Radiation Oncology*Biology*Physics | 2010 | 8 Pages |
Abstract
A significant down-regulation of proteins and an increase in protein markers of apoptosis were observed at the onset of lung injury in the irradiated rat lung. Treatment with MnTE-2-PyP5+, which has been demonstrated to reduce lung injury from radiation, reduced apparent protein degradation and apoptosis indicators, suggesting that preservation of lung structural integrity and prevention of cell loss may underlie the radioprotective effect of this compound.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Vasily A. M.D., Ph.D., Christopher S. B.S., Heidi Ph.D., Ben M.D., Katharina M.D., Ines Ph.D., Isabel B.S., Zeljko M.D., Ph.D., Mitchell S. M.D., Ross B. Ph.D., Paul R. Ph.D.,