Article ID Journal Published Year Pages File Type
8232572 International Journal of Radiation Oncology*Biology*Physics 2010 9 Pages PDF
Abstract
The data confirm that HRS is linked to the early G2/M checkpoint through the damage response of G2-phase cells. Low-dose radiosensitivity could be increased by manipulating the transition of radiation-damaged G2-phase cells into mitosis. This provides a rationale for combining low-dose radiation therapy with chemical synchronization techniques to improve increased radiosensitivity.
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Related Topics
Physical Sciences and Engineering Physics and Astronomy Radiation
Preview
The Effects of G2-Phase Enrichment and Checkpoint Abrogation on Low-Dose Hyper-Radiosensitivity
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