Inhibition of STAT3 and ErbB2 Suppresses Tumor Growth, Enhances Radiosensitivity, and Induces Mitochondria-Dependent Apoptosis in Glioma Cells

Article ID	Journal	Published Year	Pages	File Type
8233030	International Journal of Radiation OncologyBiologyPhysics	2010	9 Pages	PDF

Abstract

These results indicated that simultaneous inhibition of STAT3 and ErbB2 expression can promote potent antitumor activity and radiosensitizing activity in human glioma.

Keywords

ERBB2 siRNA Apoptosis signal transducers and activators of transcription Radiation

Related Topics

Physical Sciences and Engineering Physics and Astronomy Radiation

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Inhibition of STAT3 and ErbB2 Suppresses Tumor Growth, Enhances Radiosensitivity, and Induces Mitochondria-Dependent Apoptosis in Glioma Cells

Authors

Ling Ph.D., Fengsheng Ph.D., Bo B.S., Junquan Ph.D., Yalan Ph.D., Yue Ph.D., Bingzhi Ph.D., Xiaohua Ph.D.,