Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8233381 | International Journal of Radiation Oncology*Biology*Physics | 2010 | 8 Pages |
Abstract
Publications relating radiation toxicity of the optic nerves and chiasm to quantitative dose and dose-volume measures were reviewed. Few studies have adequate data for dose-volume outcome modeling. The risk of toxicity increased markedly at doses >60 Gy at â1.8 Gy/fraction and at >12 Gy for single-fraction radiosurgery. The evidence is strong that radiation tolerance is increased with a reduction in the dose per fraction. Models of threshold tolerance were examined.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Charles Ph.D., Mary K. Ph.D., Lawrence B. M.D., John M.D., Jiho M.D., John M.D., Ph.D.,