| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8233458 | International Journal of Radiation Oncology*Biology*Physics | 2010 | 8 Pages |
Abstract
These data demonstrate the suitability of Plk1 as a potential therapeutic target for HNSCC, because Plk1 depletion resulted in significant cytotoxicity in vitro and abrogated tumor-forming potential in vivo. The effects of Plk1 depletion were enhanced with the addition of RT, indicating that Plk1 represents an important potential radiation sensitizer for HNSCC.
Related Topics
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Authors
Kate Gerster, Wei M.D., M.SC., Benjamin B.SC., Shijun M.D., Emma M.SC., John M.D., F.R.C.P.C., Ralph M.D., F.R.C.P.C., Fei-Fei M.D., F.R.C.P.C.,