Is Biochemical Response More Important Than Duration of Neoadjuvant Hormone Therapy Before Radiotherapy for Clinically Localized Prostate Cancer? An Analysis of the 3- Versus 8-Month Randomized Trial

Article ID	Journal	Published Year	Pages	File Type
8233727	International Journal of Radiation OncologyBiologyPhysics	2010	8 Pages	PDF

Abstract

Biochemical response to neoadjuvant ADT before RT, not duration, appears to be the critical determinant of benefit in the setting of combined therapy. Individually tailored ADT duration based on PRPH-PSA would maximize therapeutic gain, while minimizing the duration of ADT and its related toxicities.

Keywords

Prostate specific antigen (PSA)Prostate radiotherapy Prostate cancer

Related Topics

Physical Sciences and Engineering Physics and Astronomy Radiation

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Is Biochemical Response More Important Than Duration of Neoadjuvant Hormone Therapy Before Radiotherapy for Clinically Localized Prostate Cancer? An Analysis of the 3- Versus 8-Month Randomized Trial

Authors

Abraham M.D., F.R.C.P.C., Juanita M.D., F.R.C.P.C., Stuart B.Sc., Shawn M.D., F.R.C.P.C., Julie M.D., F.R.C.P.C., Pauline M.D., F.R.C.P.C., Howard M.D., F.R.C.P.C., Charles M.D., F.R.C.P.C.,