| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8235041 | International Journal of Radiation Oncology*Biology*Physics | 2009 | 6 Pages |
Abstract
S-phase cells are more sensitive to high-LET IR than nonsynchronized and G2-phase cells, because of the following mechanism: it is more difficult for Ku protein to bind to high-LET IR-induced DNA DSBs in S-phase cells than in cells at other phases, which results in less efficient NHEJ.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Hongyan M.D., Shuang Ph.D., Piyan Ph.D., Shimeng Ph.D., Mamta Ph.D., Huichen Ph.D., Ya M.D., Ph.D.,