| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8235093 | International Journal of Radiation Oncology*Biology*Physics | 2009 | 10 Pages |
Abstract
COX-2 appears to prolong IR-induced G2 arrest by upregulating ATR. Celecoxib downregulated ATR preferentially in irradiated COX-2 overexpressing cells. Celecoxib may radiosensitize cancer cells by inhibiting G2 arrest through ATR downregulation.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Hyun Jung M.Sc., Young Mee Ph.D., Soo Yeon B.Sc., Ji Sun M.Sc., Eun Jung M.Sc., Shin Ae M.Sc., Hongryull M.D., Ph.D.,