| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8236046 | International Journal of Radiation Oncology*Biology*Physics | 2009 | 10 Pages |
Abstract
Nuclear overexpression of survivin was associated with improved overall and prostate cancer survival on multivariate analysis, and cytoplasmic overexpression of survivin was associated with increased rate of local progression on univariate analysis in patients with locally advanced prostate cancer treated on RTOG 8610. Our results might reflect the different functions of survivin and its splice variants, which are known to exist in distinct subcellular compartments.
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Authors
Min M.D., Ph.D., Alex B.S., Elizabeth H. M.D., Yoshiyuki M.D., Ph.D., R. Scott M.D., R. Jeffrey M.D., Michael M.D., William U. M.D., Howard M.D., Li-Yan M.D., Alan M.D., Ph.D., Arnab M.D.,