Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8236990 | International Journal of Radiation Oncology*Biology*Physics | 2009 | 8 Pages |
Abstract
This approach is promising for patients with bone sarcomas in which resection will likely yield close/positive margins. It appears to inhibit tumor seeding with an acceptable rate of wound-healing complications. Dose escalation is accomplished without high-dose preoperative radiation (likely associated with higher rates of acute wound healing delays) or large-field postoperative radiation only (likely associated with late normal tissue toxicity). The LC and DFS rates are substantially better for patients with primary than recurrent sarcomas.
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Authors
Timothy D. M.D., M.B.A., Wendy B.A., Susan B.S., Saveli I. Ph.D., David G. M.D., Ph.D., Herman D. M.D., D.Phil., Francis J. M.D., Ph.D., Francis X. M.D., Kevin A. M.D., Dempsey S. M.D., Sam S. M.D., Marc C. M.D., Henry J. M.D., Thomas F. M.D.,