| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8237983 | International Journal of Radiation Oncology*Biology*Physics | 2008 | 8 Pages |
Abstract
The results of this study have demonstrated the initial proof of principle for the MRT approach for designing targeted α-particle emitting radiotherapeutic agents. The high cytotoxicity of SAGMB-MRT for cancer cells overexpressing EGFR suggests that this 211At-labeled conjugate has promise for the treatment of malignancies, such as glioma, which overexpress this receptor.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Andrey A. Ph.D., Ganesan Ph.D., Oscar R. Ph.D., Vladimir G. Ph.D., Michael R. Ph.D., Alexander S. Ph.D.,