Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8238157 | International Journal of Radiation Oncology*Biology*Physics | 2008 | 11 Pages |
Abstract
Flavopiridol enhanced the cytotoxic effect of radiation in radioresistant tumor cells that harbor p53 dysfunction or Bcl-2 overexpression. A combination treatment of flavopiridol with radiation has the potential to conquer the radioresistance of malignant tumors induced by the genetic alteration of p53 or bcl-2.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Takamitsu Ph.D., Motoko M.D., Ph.D., Yun M.D., Ph.D., Chao M.D., Tomio M.D., Ph.D.,