Effects of Respiration-Averaged Computed Tomography on Positron Emission Tomography/Computed Tomography Quantification and its Potential Impact on Gross Tumor Volume Delineation

This study benchmarked the differences between the PET data with and without artifacts. It is important to pay attention to the potential existence of these artifacts during GTV contouring, as such artifacts may increase the uncertainties in the lesion volume and the centroid location.