Early Mucosal Reactions During and After Head-and-Neck Radiotherapy: Dependence of Treatment Tolerance on Radiation Dose and Schedule Duration

All schedules analyzed (regular, gap, and accelerating) with BEDCK values below BEDCKboundary(T)=69.5×(T/32.2)/sin((T/32.2)(radians))−3.5Gy10(forT≤50 days) are tolerable, and many lying above the boundary are intolerable. The accelerating schedules analyzed were tolerated better overall than are the regular schedules with similar [BEDCK,T] values.