Article ID Journal Published Year Pages File Type
8239504 International Journal of Radiation Oncology*Biology*Physics 2008 9 Pages PDF
Abstract
The acute and subacute changes in normal-appearing white matter fibers indicate radiation-induced demyelination and mild structural degradation of axonal fibers. The structural changes after RT are progressive, with early dose-dependent demyelination and subsequent diffuse dose-independent demyelination and mild axonal degradation. Diffusion tensor magnetic resonance imaging is potentially a biomarker for the assessment of radiation-induced white matter injury.
Related Topics
Physical Sciences and Engineering Physics and Astronomy Radiation
Authors
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