Reduction of Overall Treatment Time in Patients Irradiated for More Than Three Brain Metastases

Shorter course WBRT with 5 × 4 Gy was associated with similar survival and local control as “standard” WBRT with 10 × 3 Gy in patients with more than three brain metastases. The 5 × 4-Gy regimen appears preferable for most of these patients, because it is less time consuming and more convenient for patients than the 10 × 3-Gy regimen.