Predictors for Chronic Urinary Toxicity After the Treatment of Prostate Cancer With Adaptive Three-Dimensional Conformal Radiotherapy: Dose-Volume Analysis of a Phase II Dose-Escalation Study

Acute urinary toxicity and bladder wall dose-volume endpoints are strong predictors for the development of subsequent chronic urinary toxicity. Our recommendation is to attempt to limit the bladder wall V30 to <30 cm3 and the V82 to <7 cm3 when possible. If bladder wall information is not available, bladder solid V30 and V82 may be used.