Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8241217 | International Journal of Radiation Oncology*Biology*Physics | 2007 | 7 Pages |
Abstract
Growth in the co-culture assay reflects the transformation status and provides a useful in vitro model for assessing invasiveness. Human glioma invasiveness in the co-culture model responds variably to single low-dose fractions. MMP activity promotes invasiveness in the co-culture model. Reduced invasiveness in irradiated U251 appears to be mediated by MMP-independent mechanisms.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Jean L. M.D., Daphne A. M.D., Russell O. Ph.D.,