Evaluation of Uncertainty-Based Stopping Criteria for Monte Carlo Calculations of Intensity-Modulated Radiotherapy and Arc Therapy Patient Dose Distributions

For the patient cases studied, the MC calculations using PTV-stopping criteria only allowed accurate treatment plan evaluation. The proposed stopping criteria provided a flexible tool to assist MC patient dose calculations. The structures of interest and appropriate values of σrel,tol and Dlim should be selected for each patient individually according to the clinical treatment planning goals.