| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8241645 | International Journal of Radiation Oncology*Biology*Physics | 2007 | 7 Pages |
Abstract
We have demonstrated a DNA-PKcs-dependent differential modulation of cellular radiosensitivity by celecoxib. These effects might be attributed to alterations in signaling cascades downstream of DNA-PK toward cell survival. These findings offer an explanation for the poor outcomes in some recently published clinical trials.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Elisabeth M.D., Reinhard M.D., Benjamin P. Ph.D., David J. Ph.D., Keiko M.Eng., Hak M.D., Debabrata Ph.D.,