| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8243541 | International Journal of Radiation Oncology*Biology*Physics | 2007 | 6 Pages |
Abstract
Conclusions: Fluctuating pO2 reduced the concentration of metabolized TPZ at distances farther from the source, thereby limiting its ability to reach and kill the most hypoxic cells. These results suggest that the kinetics of fluctuating oxygenation should be taken into account when considering drug designs that involve oxygen-sensitive agents.
Keywords
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
L. Isabel B.S., Timothy W. Ph.D., Mark W. D.V.M., Ph.D.,