Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8243745 | International Journal of Radiation Oncology*Biology*Physics | 2006 | 10 Pages |
Abstract
Conclusions: Biochemical failure definitions applying a PSA threshold at or after the nadir (e.g., threshold 3) demonstrated the highest association with CF, OS, and CSS for all assessed treatment modalities. Definitions incorporating a PSA increase above the nadir value (e.g., nadir + 2 ng/mL) were also superior for all modalities. In general, BF definitions have greater predictive capacity for clinical outcome with brachytherapy or neoadjuvant AD than EBRT alone, possibly because of less “noise” from production of background PSA.
Keywords
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Authors
Dwight L. M.D., Samuel M.D., Alvaro A. M.D., Frank A. M.D., Larry L. M.D.,