Single-nucleotide polymorphisms in base excision repair, nucleotide excision repair, and double strand break genes as markers for response to radiotherapy in patients with Stage I to II head-and-neck cancer

Article ID	Journal	Published Year	Pages	File Type
8243846	International Journal of Radiation OncologyBiologyPhysics	2006	9 Pages	PDF

Abstract

Conclusions: Genetic polymorphisms in XPF/ERCC1, XPG/ERCC5, and XPA may significantly influence response to radiotherapy; large studies are warranted to confirm their role in HNSCC.

Keywords

DNA repair Radiotherapy Head-and-neck cancer Single-nucleotide polymorphism

Related Topics

Physical Sciences and Engineering Physics and Astronomy Radiation

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Single-nucleotide polymorphisms in base excision repair, nucleotide excision repair, and double strand break genes as markers for response to radiotherapy in patients with Stage I to II head-and-neck cancer

Authors

Joan M.D., Ph.D., Mariano M.D., Ph.D., Marta M.D., Ph.D., Sonia Ph.D., Rosa Ph.D., Alfons Ph.D., Palmira M.D., Ph.D., Francesc M.D., Ph.D., Angel M.D., Ph.D., Bernat Ph.D., Maribel M.D., Ph.D., Joan M.D., Ph.D., Xavier M.D., Ph.D.,