Radiochemotherapy combined with regional pelvic hyperthermia induces high response and resectability rates in patients with nonresectable cervical cancer ≥FIGO IIB “bulky”

Conclusion: Preoperative hyperthermic radiochemotherapy (45-50 Gy) induces high response rates and enables curative surgery in a high proportion of patients with nonresectable cervical cancer. Therefore, the use of hyperthermia in conjunction with standard chemo-/radiotherapy ± surgery may allow for more effective tumor treatment while decreasing the risk of complications in patients with locally advanced cervical cancer.