Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8244227 | International Journal of Radiation Oncology*Biology*Physics | 2006 | 9 Pages |
Abstract
Conclusion: Our data show that together with an overall decrease in tumor cell and endothelial cell proliferation, RTX results in an increase in the expression of adhesion molecules that stimulate leukocyte infiltration. This suggests the possibility that, in addition to its direct cytotoxic effect, radiation may also stimulate an immunologic tumor response that could contribute to the documented improvement in local tumor control and distal failure rate of rectal cancers.
Related Topics
Physical Sciences and Engineering
Physics and Astronomy
Radiation
Authors
Coen I.M. M.D., Karolien M.B., Guido M.D., Ph.D., Femke M.B., Bradly G. Ph.D., Harry F.P. M.D., Ph.D., Arjan W. Ph.D., Cornelius G.M.I. M.D., Ph.D.,