Final results of a Phase I/II dose escalation trial in non-small-cell lung cancer using three-dimensional conformal radiotherapy

Article ID	Journal	Published Year	Pages	File Type
8244884	International Journal of Radiation OncologyBiologyPhysics	2006	9 Pages	PDF

Abstract

Conclusion: Dose escalation is safe up to 94.5 Gy in 42 fractions in 6 weeks in patients with an MLD 13.6 Gy or less. Higher doses are associated with a better FFI and OS for smaller tumor volumes. Involved-field irradiation results in a low percentage of isolated nodal relapses.

Keywords

Dose escalation Non–small-cell lung cancer Mean lung dose Conformal radiotherapy Radiation pneumonitis

Related Topics

Physical Sciences and Engineering Physics and Astronomy Radiation

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Final results of a Phase I/II dose escalation trial in non-small-cell lung cancer using three-dimensional conformal radiotherapy

Authors

Jose S.A. M.D., Wilma D. Ms.C., Katrien M.D., Ph.D., Paul M.D., Ph.D., Joos V. M.D., Ph.D.,