Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8247816 | International Journal of Radiation Oncology*Biology*Physics | 2006 | 7 Pages |
Abstract
Conclusions: This study suggests that the probability of neurotoxicity is a relatively steep function of dose to cauda equina (slope γ50 = approximately 3). The cauda equina tolerance is greater for females than males by about 11 CGE (at 2 CGE per fraction). Extended follow-up is necessary to accurately assess neurologic damage and then differentiate that phenomenon from local recurrence; the traditional 5-year assessment has limited meaning in this population. Local control remains an issue for these patients, even with the radical doses used.
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Authors
Richard S. M.D., Andrzej Ph.D., Barbara C. Ph.D., John E. M.D.,