Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8248672 | Physica Medica | 2018 | 6 Pages |
Abstract
The gold standard and the simplified geometrical model gave similar dosimetry results (dose differenceâ¯<â¯3.5%), indicating that the latter can be considered as a satisfactory approximation of the real geometry. In contrast, the sphere model systematically overestimated the absorbed dose compared to both Monte Carlo models (range: 4-50% dose difference), depending on the isotope energy and organ mass. Therefore, the simplified geometric model was adopted to introduce an analytical approach for choroid plexuses dosimetry in the mass range 2-16â¯g. The proposed model enables the estimation of the choroid plexuses dose by a simple bi-parametric function, once the organ mass and the residence time of the radiopharmaceutical under investigation are provided.
Related Topics
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Authors
Ernesto Amato, Francesco Cicone, Lucrezia Auditore, Sergio Baldari, John O. Prior, Silvano Gnesin,