| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8258440 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2018 | 43 Pages |
Abstract
UPR and autophagy are increased in EAT compared to SAT, opening doors to the identification of early biomarkers for cardiomyopathies and novel therapeutic targets.
Keywords
LVEFBcl-2SATECFECLPINK1UPRLC3GRPp62AMPKNYHAmTORC1GADD153ULK1LAMP2NDMBECN1NCADLVSFFFAmTORCCSPVDFERADIRE1αmTOR complex 1PTEN-induced putative kinase 1inositol-requiring enzyme 1αAutophagyEndoplasmic reticulum stressFree fatty acidNew York Heart AssociationCanadian Cardiovascular SocietyAdipose tissueEpicardial adipose tissueSubcutaneous adipose tissueenhanced chemiluminescenceBeclin 1coronary artery diseaseCardiovascular diseasesER-Associated DegradationCHOPApoptosisEATpolyvinylidene difluorideDiabetes mellitusCVDmicrotubule-associated protein light chain 3Metabolic syndromebody mass indexBMIendoplasmic reticulumenhanced chemifluorescenceCADnon-diabeticB-cell lymphoma 2BIMheart failureMechanistic target of rapamycinUnfolded protein responseglucose-regulated proteinlysosome-associated membrane protein 2CCAAT-enhancer-binding protein homologous proteinprotein kinase RNA-like endoplasmic reticulum kinase5′ adenosine monophosphate-activated protein kinasePERKLeft ventricle ejection fraction
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Authors
A. Burgeiro, A.C. Fonseca, D. Espinoza, L. Carvalho, N. Lourenço, M. Antunes, E. Carvalho,