ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK

Article ID	Journal	Published Year	Pages	File Type
8258472	Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease	2018	64 Pages	PDF

Keywords

PHLPP1 CK1 GSK3β GLUT4 2-NBDG AS160 MEK1 inositol requiring enzyme 1 SFB PTP1B β-TrCP HFD HSD PP2A ERK IRE-1 GST tribbles-related protein 3 ATF4 spliced X-box binding protein 1 AICAR protein kinase R-like endoplasmic reticulum kinase TRB3 MAPK/ERK kinase 1 PI3K LKB1 sXBP1 AMPK AMP-activated protein kinase AUC BiP C/EBP homologous protein ER stress tumor necrosis factor alpha CHOP High fat diet High sucrose diet TNF-α Phosphatidylinositol 3-kinase activating transcription factor 4 Insulin resistance area under the curve Glucose transporter type 4 wild type hemagglutinin Binding immunoglobulin Protein Protein tyrosine phosphatase 1B protein phosphatase 2 PERK casein kinase 1 liver kinase B1 Extracellular signal–regulated kinases glutathione S-transferase glycogen synthase kinase-3 beta

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ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK

Authors

Soma Behera, Bandish Kapadia, Vasundhara Kain, Neeraja P. Alamuru-Yellapragada, Vachana Murunikkara, Sireesh T. Kumar, Phanithi Prakash Babu, Sriram Seshadri, Prasad Shivarudraiah, Jagadheshan Hiriyan, Narmadha Reddy Gangula, Subbareddy Maddika,