| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8258512 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2018 | 7 Pages |
Abstract
Not only the stimulation of TGR5-mediated pathways by suitable TGR5 agonists but also the inhibition of TGR5 signalling by the use of antagonists represent potential therapeutic approaches for different types of biliary diseases. This article is part of a Special Issue entitled: Cholangiocytes in Health and Disease edited by Jesus Banales, Marco Marzioni, Nicholas LaRusso and Peter Jansen.
Keywords
DCAG protein-coupled bile acid receptor 1TLCAGCDCAMdr2CD95LTCDCATGR5CBDLBSEPMDR3CDCAS1PR2CFTRGPCRCCAEGFRMMPEGFTCAcyclic AMPcAMPMAPKadenylate cyclasepolycystic liver diseaseKupffer cellsepidermal growth factorCD95 ligandmatrix metalloproteinaseBile saltmitogen-activated protein kinasecommon bile duct ligationCholangiocarcinomaSphingosine-1-phosphate receptor 2Bile acid receptorEpidermal growth factor receptorG protein-coupled receptor
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Authors
Kathleen Deutschmann, Maria Reich, Caroline Klindt, Carola Dröge, Lina Spomer, Dieter Häussinger, Verena Keitel,