| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8258668 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2018 | 34 Pages |
Abstract
Lentivirus mediated UHMK1 knockdown did not affect proliferation, cell cycle progression, apoptosis or migration of U937 leukemia cells, although UHMK1 silencing strikingly increased clonogenicity of these cells. Thus, our results suggest that UHMK1 plays a role in hematopoietic cell differentiation and suppression of autonomous clonal growth of leukemia cells.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Ageing
Authors
Isabella Barbutti, João Agostinho Machado-Neto, Vanessa Cristina Arfelli, Paula de Melo Campos, Fabiola Traina, Sara Teresinha Olalla Saad, Leticia Fröhlich Archangelo,