| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8258758 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2018 | 53 Pages |
Abstract
FXR, by regulating nutritional metabolism, represses autophagy in conditions of nutrient abundance, and controls the metabolic needs of proliferative cells. In addition, FXR regulates inflammation via direct effects and via its impact on nutrient metabolism. These functions indicate that FXR is an attractive therapeutic target for liver diseases.
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Authors
Vittoria Massafra, Saskia W.C. van Mil,