| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8258960 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2016 | 12 Pages |
Abstract
We discuss in detail how aberrant phosphorylation could contribute to dysregulate p53 activity and insulin-mediated signaling. Taken together these results highlight that targeted therapeutic intervention, which can restore phosphorylation homeostasis, either acting on kinases and phosphatases, conceivably may prove to be beneficial to prevent or slow the development and progression of AD.
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Authors
M. Perluigi, E. Barone, F. Di Domenico, D.A. Butterfield,