| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8259536 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2016 | 9 Pages |
Abstract
HSPA6 is a cigarette smoke-induced UC-susceptibility gene. The HSPA6 risk locus is associated with decreased HSPA6 expression. HSPA6 provides epithelial protection by stabilizing anti-apoptotic Bcl-XL, thereby contributing to the beneficial effect of cigarette smoking in UC.
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Authors
Anouk Regeling, Floris Imhann, Haukeline H. Volders, Tjasso Blokzijl, Vincent W. Bloks, Rinse K. Weersma, Gerard Dijkstra, Klaas Nico Faber,