| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8260323 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2014 | 7 Pages |
Abstract
Our data show that PP2A-C hyperphosphorylation is a frequent event that contributes to PP2A inhibition in CRC. Antitumoral effects of forskolin-mediated PP2A activation suggest that the analysis of p-PP2A-C Y307 status could be used to identify a subgroup of patients who would benefit from treatments based on PP2A activators.
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Authors
Ion Cristóbal, Raúl Rincón, Rebeca Manso, Juan Madoz-Gúrpide, Cristina Caramés, Laura del Puerto-Nevado, Federico Rojo, Jesús GarcÃa-Foncillas,