| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8260891 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 8 Pages |
Abstract
⺠Tyrosine kinases are key regulators of fibrotic tissue remodeling. ⺠Blockade of abnormal tyrosine kinase activity can inhibit experimental fibrosis. ⺠Trials with the tyrosine kinase inhibitor imatinib in IPF and SSc are inconclusive. ⺠A large RCT with the tyrosine kinase inhibitor intedanib in IPF is very promising.
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Authors
Christian Beyer, Jörg H.W. Distler,