Article ID Journal Published Year Pages File Type
8260908 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2013 8 Pages PDF
Abstract
► ER stress and the unfolded protein response contribute tofibrotic remodeling. ► ER stress enhances the susceptibility of epithelial cells to pro-fibrotic stimuli. ► ER stress facilitates fibrosis by promoting apoptosis, inflammation, and/or EMT. ► Genetic mutations, viruses, and environmental exposures may cause ER stress in vivo.
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