Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8260908 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 8 Pages |
Abstract
⺠ER stress and the unfolded protein response contribute tofibrotic remodeling. ⺠ER stress enhances the susceptibility of epithelial cells to pro-fibrotic stimuli. ⺠ER stress facilitates fibrosis by promoting apoptosis, inflammation, and/or EMT. ⺠Genetic mutations, viruses, and environmental exposures may cause ER stress in vivo.
Keywords
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Authors
Harikrishna Tanjore, William E. Lawson, Timothy S. Blackwell,