Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8260935 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 13 Pages |
Abstract
⺠TLRs detect pathogen-associated molecular patterns. ⺠In tissue injury, TLRs may also detect endogenous molecular “danger” patterns. ⺠TLRs are expressed not only on immune cells but also on fibroblasts and epithelium. ⺠TLRs promote maladaptive wound healing responses such as fibrosis and carcinogenesis. ⺠The contribution of TLRs to wound healing is highly organ- and context-dependent.
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Authors
Peter Huebener, Robert F. Schwabe,