Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8260974 | Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease | 2013 | 9 Pages |
Abstract
⺠The liver lymphocyte population is enriched with NK and NKT cells. ⺠NK cells inhibit liver fibrosis by killing activated HSCs and by producing IFN-γ. ⺠IFN-α therapy enhances, while alcohol and TGF-β inhibit, NK cell killing of HSCs. ⺠NKT cells produce pro-fibrotic cytokines to promote liver fibrosis. ⺠NKT cells also produce anti-fibrotic cytokines to inhibit liver fibrosis.
Keywords
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Authors
Bin Gao, Svetlana Radaeva,